Primary Immunodeficiencies: From Early Diagnosis and Gene Discovery to Personalized Therapy
Grant Amount: NIS 6.2 Million
About the Project
Biology and medicine are undergoing a tremendous revolution in which the use of advanced technologies, sophisticated bioinformatics and big data can immediately impact disease diagnosis, treatment and outcome. Thus, the main objective of this project, which combines clinical and basic scientific skills, is to extend our knowledge of the pathways controlling human immunity in early life, to increase the number of primary immunodeficiency diseases to be diagnosed early in life, to understand new disease patho-mechanisms, and to develop a novel and personalized gene-based treatment.
Research Team
Prof. Raz Somech
Chaim Sheba Medical Center, Edmond and Lily Safra Children's Hospital, Pediatric Department and Pediatric Immunology
​Dr. Yu Nee Lee
Chaim Sheba Medical Center, Immunology
​Dr. Ayal Hendel
Bar-Ilan University, Mina and Everard Goodman Faculty of Life Sciences
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